Study finds how gut microbes play role in regulating stress responsiveness throughout day
Groundbreaking Study Reveals Gut Bacteria's Role in Stress Management
Introduction
A new study from University College Cork and APC Microbiome Ireland has discovered the crucial role of gut bacteria in managing stress through interactions with the body's circadian rhythms. This research could lead to new microbial-based medicines to help with stress-related mental health issues like anxiety and depression.
Key Findings
The study, published in Cell Metabolism, highlights the relationship between gut microbiota and the hypothalamic-pituitary-adrenal (HPA) axis, the body's main stress response system. It shows that a lack of gut microbiota can cause an overactive HPA-axis, affecting stress responses throughout the day.
Specific Bacteria Identified
Researchers identified specific gut bacteria, including a strain of Lactobacillus (Limosilactobacillus reuteri), as key players in this stress mechanism. L. reuteri was found to influence stress hormone secretion, linking natural microbiota rhythms with stress response changes.
Implications for Mental Health
This discovery opens up possibilities for psychobiotic treatments targeting gut bacteria to improve mental health. With modern lifestyles often disrupting circadian rhythms, this research emphasizes the importance of gut microbiota in stress regulation.
Expert Opinions
Professor John Cryan, the Principal Investigator, stated, "Our research shows an important link between gut microbiota and stress response, following a precise circadian rhythm." Dr. Gabriel Tofani added, "Our findings highlight the importance of gut microbiota composition and its daily changes in stress management." Professor Paul Ross, Director of APC Microbiome Ireland, noted, "This study is a significant step in understanding how the microbiome affects mental health."
Doubts Revealed
University College Cork
University College Cork is a university in Ireland. It is known for its research and education in various fields.
APC Microbiome Ireland
APC Microbiome Ireland is a research center that studies the microorganisms living in our bodies, especially in the gut. They focus on how these tiny organisms affect our health.
Gut Bacteria
Gut bacteria are tiny living organisms in our stomach and intestines. They help us digest food and can also affect our mood and health.
Circadian Rhythms
Circadian rhythms are natural cycles in our body that follow a 24-hour pattern. They help control when we sleep, wake up, and feel hungry.
Cell Metabolism
Cell Metabolism is a scientific journal where researchers publish their studies. It shares new discoveries about how our body's cells work.
HPA-axis
The HPA-axis is a system in our body that helps manage stress. It involves the brain and glands that release hormones to help us respond to stress.
Lactobacillus reuteri
Lactobacillus reuteri is a type of good bacteria found in the gut. It can help keep our digestive system healthy and may also influence our mood.
Psychobiotic Treatments
Psychobiotic treatments are therapies that use good bacteria to improve mental health. They aim to help people feel less stressed or anxious by balancing gut bacteria.
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